Invited Speakers

     

Mahlon R. DeLong, M.D.
Professor of Neurology
Emory Healthcare Network Physician
Emory Clinic
Member, Institute of Medicine

In a series of pioneering physiologic studies, DeLong and colleagues carried out single cell/behavioral studies that helped to clarify the functional organization of the basal ganglia and their role in movement. They identified and characterized the contribution of segregated cortical-subcortical brain circuits involving the cerebral cortex, basal ganglia and thalamus, reflecting the parallel processing of movement, executive and mood/reward functions, Subsequent studies helped to characterize the circuit disturbances underlying parkinsonism and other basal ganglia disorders and demonstrated the abolition of parkinsonism with focal inactivation of nodes of the basal ganglia motor circuit, in particular, the subthalamic nucleus. These studies, which provided novel targets, physiologic guidance and a clear rational for surgical approaches, contributed to the revival and development of neurosurgical treatments for Parkinson's and other movement disorders. DeLong and colleagues subsequently carried out clinical trials of surgical treatment for Parkinson's and other movement disorders.
DeLong is an elected member of the Johns Hopkins Society of Scholars, the Institute of Medicine and a fellow of the AAAS. His numerous awards include the AAN Movement Disorders Research Award (2009) and election as an Honorary Member of the MDS for his Extraordinary Contributions to the Advancement of Parkinson's Science (2008). Most recently he was awarded the 2013 Breakthrough Prize in the Life Sciences "for defining the interlocking circuits in the brain that malfunction in Parkinson's diseas--laying the groundwork for treatment of the disease by deep brain stimulation." Most recently he shared the 2014 Lasker~DeBakey Clinical Medical Research Award with Alim Benabid.

 

     

Tim Fayram
Vice President of Research
St. Jude Medical

Timothy A. Fayram, MS, is the Vice President of Research of St. Jude Medical Inc. Mr. Fayram previously served as St. Jude Medical Inc. Principle Engineer, Director of Technology Development, and Vice President of Mechanical Development and Principle Engineer as well as Program Manager at Ventritex Inc.
Mr. Fayram specializes in the development of early evidence that supports St. Jude Medical products and features. This evidence is generated from prospective clinical feasibility studies and observational outcomes studies from large heterogeneous data sets. This evidence-based approach identifies and addresses unmet needs in the changing healthcare environment.
Mr. Fayram earned his B.S. in Agricultural Engineering at the University of California at Davis and his M.S. in Mechanical Engineering at Stanford University. Mr. Fayram has had 33 US Patents issued, 3 journal articles authored and accepted for publication, and over 50 journal articles sponsored and accepted for publication.

 

     

Bin He, Ph.D.
Distinguished McKnight University Professor of Biomedical Engineering
Medtronic-Bakken Chair for Engineering in Medicine
Director, Institute for Engineering in Medicine
Director, Center for Neuroengineering

Bin He is a Distinguished McKnight University Professor of Biomedical Engineering, Medtronic-Bakken Endowed Chair for Engineering in Medicine, Director of the Institute for Engineering in Medicine, Director of the Center for Neuroengineering, and Director of the NSF IGERT Neuroengineering Training Program at the University of Minnesota. Dr. He's research interests cover a broad spectrum in biomedical engineering, mainly in neuroengineering and biomedical imaging. He has made significant original contributions to electrophysiological source imaging, multimodal neuroimaging, and brain-computer interface. He has published over 200 peer reviewed journal articles and is the sole editor of the text book entitled Neural Engineering (2nd Ed, 2013, Springer). Dr. He is a recipient of the Outstanding Research Award from the International Federation of Clinical Neurophysiology, the Established Investigator Award from the American Heart Association, the Distinguished Service Award from IEEE Engineering in Medicine and Biology Society (EMBS), among others. A Fellow of International Academy of Medical and Biological Engineering, IEEE, American Institute of Medical and Biological Engineering and Institute of Physics, Dr. He served as a Past President of IEEE EMBS, International Society for Functional Source Imaging, and International Society for Bioelectromagnetism. Dr. He is the Editor-in-Chief of IEEE Transactions on Biomedical Engineering, and is a member of the NIH BRAIN Multi-council Working Group.

 

     

John LaLonde
Vice President
Research, Technology and Development
Medtronic Neuromodulation

John LaLonde is the Vice President of Research, Technology and Development for Medtronic Neuromodulation.
John is an experienced medical device R&D executive with over 30 years in medical technology spanning clinical EEG and EP systems, laser scanning confocal microscopy in neuroscience, patient monitoring and neuromodulation. Prior to joining Medtronic in 2012, John was with Boston Scientific for eight years as the Vice President of R&D for Remote Patient Monitoring. John held several positions first at Nicolet Instruments and then General Electric - his last as General Manager for Global Engineering at GE Healthcare before joining Boston Scientific.
John has a Bachelor of Science Degree in Physics from the University of Minnesota Duluth, and a Master of Science Degree in Biomedical Engineering from the University of Wisconsin.

 

     

Sarah Hollingsworth Lisanby, MD
J. P. Gibbons Professor and Chair, Department of Psychiatry and Behavioral Sciences
Professor, Department of Psychology & Neuroscience
Duke University

Sarah Hollingsworth Lisanby, MD, an internationally recognized leader in the field of brain stimulation, is Professor and Chair of the Department of Psychiatry and Behavioral Sciences at Duke University School of Medicine. She is also Professor of Psychology and Neuroscience at Duke University School of Arts and Sciences.
An expert in translational research in the field of brain stimulation, Dr. Lisanby has received professional accolades for her leading role in pioneering a novel depression treatment called magnetic seizure therapy (MST), which her team took through the steps from bench to bedside, and is now at the stage of multi-center, international trials. She is the co-author on more than 150 publications in prestigious scientific journals, including The New England Journal of Medicine.
Dr. Lisanby has a distinguished academic record as a member of the FDA Neurological Devices Advisory Panel, NIH Study Sections, co-Principal Investigator of an 8-center NIH funded U01 on Prolonging Remission in Depressed Elders (PRIDE), former President of the leading international professional organizations on brain stimulation (Association for Convulsive Therapy / International Society of Neurostimulation, and the International Society for Transcranial Stimulation), and as Chair of both American Psychiatric Association committees related to brain stimulation (APA committee on ECT and the APA Task Force to Revise the Guidelines on ECT). She also co-Chairs the National Network of Depression Centers (NNDC) Task Group on transcranial magnetic stimulation (TMS).
An active researcher supported by a series of NIH, foundation, and industry grants, Lisanby directs the Duke Brain Stimulation and Neurophysiology Center that encompasses interdisciplinary research labs (spanning technology development, pre-clinical modeling, translational neuroscience, and clinical trials), clinical brain stimulation programs (including electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), vagus nerve stimulation (VNS) and deep brain stimulation (DBS)) and educational programs for trainees at all levels.
She has received many prestigious awards, including the Distinguished Investigator Award from the National Alliance for Research on Schizophrenia and Depression (NARSAD), the Max Hamilton Memorial Prize of the Collegium Internationale Neuro-Psychoharmacologicum (CINP), the Gerald Klerman Award from the National Depression and Manic Depression Association (NDMDA), and the NARSAD Klerman Award.
Dr. Lisanby earned her BS in mathematics and psychology magna cum laude at Duke University and her MD at Duke University School of Medicine in Durham, North Carolina. She completed her residency in Psychiatry at Duke University Medical Center, where she served as Executive Chief Resident. Dr. Lisanby joined Columbia in 1995 to pursue a postdoctoral research fellowship in Affective Disorders and Geriatric Psychiatry. She joined Columbia's psychiatry faculty in 1998, and was the founding director of and Therapeutic Modulation Division there from 2005-2010.

 

Kip Ludwig, Ph.D.
Program Director, Neural Engineering
National Institutes of Health, NINDS

 

Dr. Kip Ludwig joined the National Institute for Neurological Disorders and Stroke (NINDS) as the Program Director for Neural Engineering in 2011, and leads the NINDS Advanced Neural Prosthetics Research and Development Program. He received his Ph.D. in Biomedical Engineering at the University of Michigan, followed by post-doctoral work at the same institution. Dr. Ludwig's academic work included neural decoding algorithms for brain-computer interfaces (BCI), signal processing techniques to denoise neural recordings, and advanced materials to improve the chronic stimulating and recording performance of microelectrodes. More recently he worked in industry as a research scientist, where his team conceived, developed and demonstrated the chronic efficacy of a next-generation neural stimulation electrode for reducing blood pressure in both pre-clinical and clinical trials. Through this work Dr. Ludwig oversaw several good laboratory practice (GLP) and non-GLP studies supporting both European and FDA Investigational Device Exemption (IDE) human trials, as well as participated in the protocol development and execution of those trials, recently leading to approval for sale in the European Union. His interests are in all aspects of neural engineering, with special emphases on neuromodulation, BCI devices, and neural interface technology for translational development.


 

     

Michael A. Nitsche, Ph.D.
Associate Professor of Clinical Neurophysiology
Georg-August-University, Goettingen

Michael A. Nitsche is Associate Professor at the department of Clinical Neurophysiology of the Georg-August-University, Goettingen. He is the head of the laboratory of Systemic Neurosciences, and a leading expert in plasticity research in humans, including non-invasive brain stimulation, neuropsychopharmacology, and cognition. He received grants from various funding organizations, including the German Research Foundation. He published more than 100 papers in international peer-reviewed journals, and is member of the editorial board of The Journal of Neuroscience, Clinical Neurophysiology, and Restaurative Neurology and Neurosciences. He received the Alois Kornmuller, and Richard Jung Awards by the German Society of Clinical Neurophysiology, and the GESET Award by the German society of Electrostimulation and Electrotherapy for his work on non-imvasive brain stimulation in humans.

 

     

P. Hunter Peckham, Ph.D.
Donnell Institute Professor of Biomedical Engineering
Distinguished University Professor
Case Western Reserve University
Co-Director, MetroHealth Rehabilitation Institute
MetroHealth Medical Center
Member, National Academy of Engineering

P. Hunter Peckham is the Donnell Institute Professor of Biomedical Engineering and Orthopaedics, Distinguished University Professor, and Founder, Institute for Functional Restoration at Case Western Reserve University. He serves as Co-Director of the MetroHealth Rehabilitation Institute at MetroHealth Medical Center.
Dr. Peckham's research effort focuses on functional restoration of the paralyzed upper extremity in individuals with spinal cord injury. He and collaborators developed three generations of implantable neural prostheses which utilize electrical stimulation to control neuromuscular activation. They have implemented procedures to provide control upper extremity in individuals with tetraplegia, enabling individuals with central nervous system disability to regain the ability to perform essential activities of daily living. His present efforts concern technology development, expansion of the indications for this technology, and technology transfer through the non-profit Institute for Functional Restoration.
Dr. Peckham is a fellow of the American Institute of Medical and Biological Engineering, fellow and honorary member of the American Spinal Injury Association, member of the National Academy of Engineering, member of the National Academy of Inventors, and numerous professional organizations. Dr. Peckham received the Paul B. Magnuson Award, the highest honor for VA Rehabilitation Investigators. He received his undergraduate degree in Mechanical Engineering from Clarkson College of Technology (now Clarkson University), Potsdam, NY, and his MS and PhD degrees in Biomedical Engineering from Case Western Reserve University.

 

     

Carlos Peña , Ph.D.
Director
Division of Neurological and Physical Medicine Devices
Office of Device Evaluation
Center for Devices and Radiological Health
MetroHealth Medical Center
Food and Drug Administration

Dr. Carlos Peña is Division Director for the Division of Neurological and Physical Medicine Devices, in the Office of Device Evaluation, Center for Devices and Radiological Health (CDRH), at the U.S. Food and Drug Administration (FDA).
Dr. Peña is involved in all aspects of the safety and effectiveness review of neurostimulation, neurodiagnostic, neurosurgical, neurotherapeutic, and physical medicine devices. He also serves as a Principal Investigator on a FDA sponsored clinical study focused on the treatment of pediatric neurologic disorders.
Prior to joining CDRH, Dr. Peña served on detail as Assistant Director for Emerging Technologies in the Office of Science and Technology Policy (OSTP), in the Executive Office of the President of the United States. His areas of expertise included science, technology, policy, analysis, and regulatory matters related to biology, neuroscience, biotechnology, emerging technologies, agriculture, and STEM education.
Before joining OSTP/FDA, Dr. Peña served at the National Institute of Neurological Disorders and Stroke, National Institutes of Health. He completed his neurosciences doctoral training at Case Western Reserve University in Cleveland, Ohio. He also attended the University of Connecticut for the Masters in Comparative Physiology, and the City College of New York, City University of New York, where he received a Bachelors specializing in Developmental Biology.

     

Shoogo Ueno, Ph.D. (Dr. Eng.)
Professor Emeritus, the University of Tokyo
Professor/Researcher
Department of Applied Quantum Physics
Graduate School of Engineering
Professor/Researcher
Kyushu University

Shoogo Ueno received the B.S., M.S., and Ph.D. (Dr. Eng.) degrees in electronic engineering from Kyushu University, Fukuoka, Japan, in 1966, 1968, and 1972, respectively. Dr. Ueno was an Associate Professor (1976-1986) and a Professor (1986-2004) at Kyushu University. He subsequently served as a Professor in the Department of Biomedical Engineering, Graduate School of Medicine, the University of Tokyo (1994-2006). In 2006 he retired from the University of Tokyo as Professor Emeritus. Since 2006 he has been a Professor with the Department of Applied Quantum Physics, Graduate School of Engineering, Kyushu University.
Dr. Ueno's research interests are in biomagnetics and bioimaging, in particular, transcranial magnetic stimulation, electro- and magneto-encephalography, magnetic resonance imaging, magnetic control of cell growth, and electromagnetic treatments of brain diseases.
Dr. Ueno is a Life Fellow of the Institute of Electrical and Electronics Engineers, IEEE (2011), a Fellow of the American Institute for Medical and Biological Engineering, AIMBE (2001). He is a Fellow (2006) and Secretary (2012) of the Governing Council of the International Academy of Medical and Biological Engineering, IAMBE. Dr. Ueno was President of the Bioelectromagnetics Society (2003-2004), Chairman of the Commission K on Electromagnetics in Biology and Medicine of the International Union of Radio Science (URSI) (2000-2003). He received the Doctor Honoris Causa from Linkoping University, Sweden (1998), and also received a 150th Anniversary Jubilee Visiting Professor at Chalmers University of Technology, Sweden (2006). Dr. Ueno was awarded the IEEE Magnetics Society Distinguished Lecturer during 2010 and d'Arsoncval Medal from the Bioelectromagnetics Society (2010).

 

     
Jerrold L. Vitek, M.D., Ph.D.
Professor and Head
Department of Neurology
University of Minnesota
 

Jerrold L. Vitek is Professor and Head of the Department of Neurology at the University of Minnesota. Dr. Vitek received his medical degree as well as a doctorate of neurophysiology from the University of Minnesota in 1984 and completed his residency in Neurology at The Johns Hopkins Hospital. In 1988, Dr. Vitek accepted a faculty position in the Department of Neurology at the Johns Hopkins University School of Medicine. There, he spent two years studying motor systems in animal models of Parkinson's disease (PD) and worked with Drs. F. Lenz and M. DeLong to establish the functional neurosurgery program at the Johns Hopkins Hospital. In 1990, he accepted a position at Emory University School of Medicine in Atlanta, GA to develop and direct the program for functional and stereotactic neurology. During that time, his program gained both national and international recognition. While at Emory, he also ran a basic science laboratory directed at studying the pathophysiology of Parkinson's disease and other movement disorders and delineating the mechanism(s) underlying the beneficial effects of deep brain stimulation (DBS). From Emory, he went on to the Cleveland Clinic where he continued to serve as a practicing physician in the field of movement disorders and deep brain stimulation and became the Director of the Neuromodulation Research Center. This center focused on the development of new applications for DBS, improving current application and advancement of functional surgery and DBS techniques for the treatment of neurological disease. Dr. Vitek accepted the Chair of Neurology position at the University of Minnesota in June of 2010 where he continues to see patients specializing in the diagnosis, treatment and management of movement disorders, performing electrophysiology and mapping during DBS surgery and DBS programming. Dr. Vitek is also the Director for the Center for Neuromodulation Research at the University of Minnesota and a principal investigator on numerous basic, preclinical and clinical studies investigating the pathophysiology of movement disorders, mechanisms of DBS and the application of DBS for the treatment of neurologic disorders.


 

     
Beth Winkelstein, Ph.D.
Professor
Department of Bioengineering
Associate Dean for Undergraduate Education
School of Engineering and Applied Science
University of Pennsylvania
Beth Winkelstein is Professor of Bioengineering and Professor of Neurosurgery, as well as Associate Dean for Undergraduate Education in the School or Engineering and Applied Science, at the University of Pennsylvania.
Dr. Winkelstein's research focuses on defining mechanisms of painful spine and joint injuries, mechanical and cellular mechanisms of chronic pain, mechanotransduction of pain signals, and potential diagnostic and therapeutic approaches for these disorders. She has pioneered several rat models of painful tissue injuries, which are the first neck injury models with clinically-relevant pain symptoms. Her group implements rigorous engineering analyses in these in vivo systems to define biomechanical loading and relate those metrics to neuronal plasticity and cellular mechanisms that drive pain. Her group also is developing new imaging approaches in ligament tissue biomechanics studies to understand subfailure micro- and macro-scale tissue responses.
Dr. Winkelstein's research has been recognized by awards from the Stapp Car Crash Conference, the International Society for the Study of the Lumbar Spine, the Cervical Spine Research Society and the ASME. She was awarded a Whitaker Young Investigator Award, an NIH Career Award, the NSF CAREER Award, and the 2006 YC Fung Young Investigator Award for the most promising young Bioengineer.
She serves on the Editorial Board for Spine and is the Co-Editor of the Journal of Biomechanical Engineering. She has published over 95 peer-reviewed papers, 15 book chapters and 1 book on Orthopaedic Biomechanics.

 

 

 

 

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